Stabil Kronik Obtrüktif Akciğer Hastalığı Hastalarında Serum Prolidaz ve Karbonik Anhidraz III Düzeylerinin Klinik Önemi

Aim: Chronic obstructive pulmonary disease (COPD) is a characterized by irreversible airway flow limitation and chronic inflammation. We aimed to investigate the clinical importance of serum prolidase enzyme, which an indicator collagen degradation, Carbonic anhydrase (CA) III has important function in acid-base regulation, patients with COPD Methods : In this study, 56 stable 32 healthy subjects without smoking history comorbidities were included. Serum CA enzyme levels compared between two groups. Results: The statistical difference was not found groups terms (p=0.831). There statistically significant increase group (p=0.001). moderate positively correlation CAIII partial pressure carbon dioxide blood (pCO2) negatively oxygen (pO2) (r:0.302, p<0.025; r:-0.314, p:0.02). Conclusions: think that there relationship COPD, therefore, may be candidate biomarker follow-up COPD.